Poster Session

Presenter Information

Stephanie Daniell, UNGFollow

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Faculty Mentor(s)

Jeremy Olson

Campus

Dahlonega

Proposal Type

Poster

Subject Area

Chemistry

Start Date

17-4-2020 12:00 PM

End Date

17-4-2020 1:00 PM

Description/Abstract

Caged organic molecules provide an opportunity to selectively switch certain reaction pathways on and off. These compounds have a photochemical protecting group that renders the compound inactive. By exposing these compounds to light, one can uncage the compound by removing the protecting group and thus “turn on” these pathways. Proline is an organocatalyst, which has many uses in C-C/C-X bond formation and C-H bond activation. Caged proline was previously synthesized with 4-carboxy-5,7-dinitroindolinyl (CDNI), a photocleavable protecting group, which was shown to work well at short wavelengths. By using a functionalized coumarin system, one can shift the absorbance to the visible light region, increasing the synthetic usefulness of these caged organocatalysts.

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Apr 17th, 12:00 PM Apr 17th, 1:00 PM

14. Visible Light Uncaging of Proline

Caged organic molecules provide an opportunity to selectively switch certain reaction pathways on and off. These compounds have a photochemical protecting group that renders the compound inactive. By exposing these compounds to light, one can uncage the compound by removing the protecting group and thus “turn on” these pathways. Proline is an organocatalyst, which has many uses in C-C/C-X bond formation and C-H bond activation. Caged proline was previously synthesized with 4-carboxy-5,7-dinitroindolinyl (CDNI), a photocleavable protecting group, which was shown to work well at short wavelengths. By using a functionalized coumarin system, one can shift the absorbance to the visible light region, increasing the synthetic usefulness of these caged organocatalysts.